5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine

Fa'amatalaga Puupuu:

CAS: 330786-24-8

MF: C₁₇H₁₃N₅O

MW: 303.32

EINECS: 810-090-0

Vaega o oloa: Ibrutinib;Fa'ama'i kanesa

Auina imeli ia matou

Fa'amatalaga Oloa

Faailoga o oloa

Synonyms

5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine

4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine

3-(4-phenoxy-phenyl)-1(2)H-pyrazole

3-(4-phenoxyphenyl)-1H-pyrazole

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

3-[4-phenoxyphenyl]pyrazole

Ibrutinib N-2

3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-D]pyrimidine-4-amine

1H-Pyrazolo[3,4-d]pyrimidin-4-amine,

Meatotino Physico-chemical

Fuafua mole	C5H8O3
Misasa Molar	116,115 g / mol
Malosi	1.262g/cm³
Fa'ailoga Tulaga	243.2°C ile 760 mmHg
Mata'imu	113.2°C
Ausa Malo	0.0107mmHg ile 25°C
Fa'asino Upu	1.48

Meatotino tau vailaau

Dmalosi: 1.380±0.06 g/cm3 (20 ºC 760 Torr),

Ssu'esu'e: E le mafai ona fa'afefeteina (1.2E-3 g/L) (25 ºC),

PSA: 89.71000

LogP: 3.97560

Fa'amatalaga Saogalemu

2.1 Fa'avasegaina o mea po'o paluga

O'ona mata'utia - Vaega 4, Tu'u gutu

2.2 Elemene fa'ailoga GHS, e aofia ai fa'amatalaga tau puipuiga

Pictogram(s)
Upu faailo	Lapataiga
Fa'amatalaga o lamatiaga	H302 E afaina pe a foloina
Fa'amatalaga puipuia
Puipuiga	P264 Fufulu ... mae'a lelei pe a uma ona tagofia. P270 Aua le 'ai, inu pe ulaula pe a fa'aogaina lenei oloa.
Tali	P301+P317 AFAI FONOINA: Maua se fesoasoani faafomai. P330 Fufulu gutu.
Teuina	leai se tasi
Lafoai	P501 Lafoa'i mea o lo'o i totonu/koneteina i se nofoaga talafeagai mo togafitiga ma lafoai e tusa ai ma tulafono ma tulafono fa'atatau, ma uiga o oloa ile taimi e lafoa'i ai.

Fa'amatalaga o oloa

Va'aiga/lanu: Efuefu Mīti, pa'epa'e i'o le lanu enaena mumu
Su'ega: 98.0%~102.0%
Tala'aga le mama:
IBR-4-m-OPh NMT 0.10%
IBR-4-o-OPh NMT 0.10%
So'o se isi NMT 0.20%
Aofa'i le mama NMT 1.0%
Fa'amama vaila'au (vaega HPLC) ≥ 99.0%
LOD (%): ≤1.0%

O matou Fa'amanuiaga:
1 O loʻo i ai a matou laisene faʻaulufale atu e faʻatagaina oe e galue faʻatasi ma le falegaosimea avanoa saʻo.
2 E a'afia i oloa mata'utia e mafai ona matou faia le tusi pasi saogalemu mo oe.
3 E talia le su'ega a isi vaega.
4 O le faʻataʻitaʻiga muamua o le uta e mafai ona ofoina atu e aunoa ma se totogi.

Muamua: (R)-(+)-2-Tetrahydrofuroic acid

Sosoo ai: (S)-1-Boc-3-hydroxypiperidine

1H-Pyrazolo[3 4-d]pyrimidin-4-amine